• Product nameAnti-Cytokeratin 16 antibody
    See all Cytokeratin 16 primary antibodies
  • Description
    Rabbit polyclonal to Cytokeratin 16
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Chimpanzee
  • Immunogen

    Synthetic peptide corresponding to a region within the internal amino acids 180-229 (AATIENAQPI LQIDNARLAA DDFRTKYEHE LALRQTVEAD VNGLRRVLDE) of human Cytokeratin 16 (NP_005548).

  • Positive control
    • Transfected 293T cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified by peptide affinity chromatography method.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab86541 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 51 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Tissue specificityExpressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis. Also found in luminal cells of sweat and mammary gland ducts.
  • Involvement in diseaseDefects in KRT16 are a cause of pachyonychia congenita type 1 (PC1) [MIM:167200]; also known as Jadassohn-Lewandowsky syndrome. PC1 is an autosomal dominant ectodermal dysplasia characterized by hypertrophic nail dystrophy resulting in onchyogryposis (thickening and increase in curvature of the nail), palmoplantar keratoderma, follicular hyperkeratosis, and oral leukokeratosis. Hyperhidrosis of the hands and feet is usually present.
    Defects in KRT16 are the cause of palmoplantar keratoderma non-epidermolytic focal (FNEPPK) [MIM:613000]. A dermatological disorder characterized by non-epidermolytic palmoplantar keratoderma limited to the pressure points on the balls of the feet, with later mild involvement on the palms. Oral, genital and follicular keratotic lesions are often present.
    Defects in KRT16 are a cause of unilateral palmoplantar verrucous nevus (UPVN) [MIM:144200]. UPVN is characterized by a localized thickening of the skin in parts of the right palm and the right sole.
    Note=KRT16 and KRT17 are coexpressed only in pathological situations such as metaplasias and carcinomas of the uterine cervix and in psoriasis vulgaris.
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Information by UniProt
  • Database links
  • Alternative names
    • CK 16 antibody
    • CK-16 antibody
    • CK16 antibody
    • Cytokeratin-16 antibody
    • Cytokeratin16 antibody
    • FNEPPK antibody
    • Focal non epidermolytic palmoplantar keratoderma antibody
    • K 16 antibody
    • K16 antibody
    • K1C16_HUMAN antibody
    • K1CP antibody
    • Keratin 1 type I antibody
    • Keratin 16 antibody
    • Keratin antibody
    • Keratin type I cytoskeletal 16 antibody
    • Keratin-16 antibody
    • Keratin16 antibody
    • KRT 16 antibody
    • Krt16 antibody
    • KRT16A antibody
    • NEPPK antibody
    • PC1 antibody
    • type I cytoskeletal 16 antibody
    see all

Anti-Cytokeratin 16 antibody images

  • Anti-Cytokeratin 16 antibody (ab86541) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 51 kDa
    Observed band size : 51 kDa

References for Anti-Cytokeratin 16 antibody (ab86541)

ab86541 has not yet been referenced specifically in any publications.

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