Overview

  • Product name
    Anti-Cytokeratin 5 + 14 antibody [16.4]
    See all Cytokeratin 5 + 14 primary antibodies
  • Description
    Mouse monoclonal [16.4] to Cytokeratin 5 + 14
  • Host species
    Mouse
  • Tested applications
    Suitable for: ICC/IF, IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation (cytokeratin enriched extract of feline tongue epithelium).

Properties

Applications

Our Abpromise guarantee covers the use of ab16570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
IHC-Fr
WB
  • Application notes
    ICC/IF: Use at an assay dependent dilution (from PubMed: 17361080)
    IHC-Fr: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Detects a band of approximately 58 and 50 kDa corresponding to cytokeratins 5 and 14 respectively.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
    • Cellular localization
      Cytoplasmic; Basal layer
    • Database links
    • Alternative names
      • CK 14 antibody
      • CK 5 antibody
      • DDD antibody
      • k14 antibody
      • k5 antibody
      • Keratin 14 antibody
      • Keratin 5 antibody
      • Keratin type I cytoskeletal 14 antibody
      • Keratin type II cytoskeletal 5 antibody
      • krt14 antibody
      • krt5 antibody
      see all

    References

    This product has been referenced in:
    • Arthur GK  et al. KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells. PLoS One 10:e0145259 (2015). Read more (PubMed: 26689552) »
    • Woodman LB  et al. Synthetic response of stimulated respiratory epithelium: modulation by prednisolone and iKK2 inhibition. Chest 143:1656-66 (2013). ICC/IF ; Human . Read more (PubMed: 23238614) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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