Overview

  • Product nameAnti-Cytokeratin 5 + 14 antibody [16.4]
    See all Cytokeratin 5 + 14 primary antibodies
  • Description
    Mouse monoclonal [16.4] to Cytokeratin 5 + 14
  • Tested applicationsSuitable for: ICC/IF, IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation (cytokeratin enriched extract of feline tongue epithelium).

Properties

Applications

Our Abpromise guarantee covers the use of ab16570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
IHC-Fr
WB
  • Application notesICC/IF: Use at an assay dependent dilution (from PubMed: 17361080)
    IHC-Fr: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Detects a band of approximately 58 and 50 kDa corresponding to cytokeratins 5 and 14 respectively.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceCytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
    • Cellular localizationCytoplasmic; Basal layer
    • Database links
    • Alternative names
      • CK 14 antibody
      • CK 5 antibody
      • DDD antibody
      • k14 antibody
      • k5 antibody
      • Keratin 14 antibody
      • Keratin 5 antibody
      • Keratin type I cytoskeletal 14 antibody
      • Keratin type II cytoskeletal 5 antibody
      • krt14 antibody
      • krt5 antibody
      see all

    References for Anti-Cytokeratin 5 + 14 antibody [16.4] (ab16570)

    This product has been referenced in:
    • Woodman LB  et al. Synthetic response of stimulated respiratory epithelium: modulation by prednisolone and iKK2 inhibition. Chest 143:1656-66 (2013). ICC/IF ; Human . Read more (PubMed: 23238614) »
    • Stenzinger A  et al. Epidermal growth factor-, transforming growth factor-beta-, retinoic acid- and 1,25-dihydroxyvitamin D3-regulated expression of the novel protein PTPIP51 in keratinocytes. Cells Tissues Organs 184:76-87 (2006). Read more (PubMed: 17361080) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab16570.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"