Overview

  • Product nameAnti-Cytokeratin 6a antibody
    See all Cytokeratin 6a primary antibodies
  • Description
    Rabbit polyclonal to Cytokeratin 6a
  • Tested applicationsSuitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Does not react with: Rat
  • Immunogen

    Synthetic peptide within Human Cytokeratin 6a aa 1-100 (N terminal). The exact sequence is proprietary.

  • Positive control
    • WB: A431 cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab52869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 60 kDa).
Flow Cyt 1/15. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • Tissue specificityConstitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
  • Involvement in diseaseDefects in KRT6A are a cause of pachyonychia congenita type 1 (PC1) [MIM:167200]; also known as Jadassohn-Lewandowsky syndrome. PC1 is an autosomal dominant ectodermal dysplasia characterized by hypertrophic nail dystrophy resulting in onchyogryposis (thickening and increase in curvature of the nail), palmoplantar keratoderma, follicular hyperkeratosis, and oral leukokeratosis. Hyperhidrosis of the hands and feet is usually present.
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Information by UniProt
  • Database links
  • Alternative names
    • CK-6A antibody
    • CK-6D antibody
    • CK6A antibody
    • CK6C antibody
    • CK6D antibody
    • Cytokeratin-6A antibody
    • Cytokeratin-6D antibody
    • K2C6A_HUMAN antibody
    • K6A antibody
    • K6C antibody
    • K6D antibody
    • keratin 6A antibody
    • Keratin antibody
    • Keratin, type II cytoskeletal 6A antibody
    • Keratin-6A antibody
    • Krt6a antibody
    • KRT6C antibody
    • KRT6D antibody
    • type II cytoskeletal 6A antibody
    • Type-II keratin Kb6 antibody
    see all

Anti-Cytokeratin 6a antibody images

  • Anti-Cytokeratin 6a antibody (ab52869) at 1/500 dilution + A431 cell lysate at 10 µg

    Secondary
    Goat anti-rabbit HRP at 1/2000 dilution

    Predicted band size : 60 kDa
    Observed band size : 56 kDa (why is the actual band size different from the predicted?)

References for Anti-Cytokeratin 6a antibody (ab52869)

ab52869 has not yet been referenced specifically in any publications.

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