The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/200.
FunctionBlocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Tissue specificityExpressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
Sequence similaritiesBelongs to the intermediate filament family.
Post-translational modificationsArg-20 is dimethylated, probably to asymmetric dimethylarginine.
Immunohistochemical analysis of paraffin-fixed, formalin-embedded breast carcinoma showing cytoplasmic staining with ab90083 at a dilution of 1/100: (A) without immunizing peptide, (B) with blocking immunizing peptide
References for Anti-Cytokeratin 7 antibody (ab90083)
This product has been referenced in:
Guinot A et al. miR-17-92/p38a Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res76:4012-22 (2016).
IHC (PFA fixed)
Read more (PubMed: 27197183) »