Overview

  • Product nameAnti-Cytokeratin 7 antibody [CK-7]
    See all Cytokeratin 7 primary antibodies
  • Description
    Mouse monoclonal [CK-7] to Cytokeratin 7
  • SpecificityNo cross reactivity with other proteins.
  • Tested applicationsSuitable for: WB, IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human Cytokeratin 7. Cytoskeletal preparation of the RT4 human bladder carcinoma cell line.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.01% Sodium azide
    Constituents: 1.2% Sodium acetate, 2% BSA
  • Concentration information loading...
  • PurityAscites
  • Purification notesab82253 is purified using goat anti-mouse IgG affinity chromatography.
  • ClonalityMonoclonal
  • Clone numberCK-7
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab82253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa.
IHC-P Use a concentration of 2 - 4 µg/ml.
IHC-Fr Use a concentration of 2 - 4 µg/ml. Fix with formalin or acetone.

Target

  • FunctionBlocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
  • Tissue specificityExpressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Post-translational
    modifications
    Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CK 7 antibody
    • CK-7 antibody
    • CK7 antibody
    • Cytokeratin 7 antibody
    • Cytokeratin-7 antibody
    • D15Wsu77e antibody
    • K2C7 antibody
    • K2C7_HUMAN antibody
    • K7 antibody
    • Keratin 7 antibody
    • Keratin 7, type II antibody
    • Keratin type II cytoskeletal 7 antibody
    • Keratin, 55K type II cytoskeletal antibody
    • Keratin, simple epithelial antibody
    • Keratin, simple epithelial type I, K7 antibody
    • Keratin, type II cytoskeletal 7 antibody
    • Keratin-7 antibody
    • Krt2-7 antibody
    • KRT7 antibody
    • MGC11625 antibody
    • MGC129731 antibody
    • MGC3625 antibody
    • Sarcolectin antibody
    • SCL antibody
    • Type II mesothelial keratin K7 antibody
    • Type-II keratin Kb7 antibody
    see all

References for Anti-Cytokeratin 7 antibody [CK-7] (ab82253)

This product has been referenced in:
  • Zhu L  et al. Surgical monotherapy may be a suitable therapeutic strategy for advanced collecting (Bellini) duct carcinoma: A case report and literature review. Exp Ther Med 12:1181-1184 (2016). IHC-P ; Human . Read more (PubMed: 27446340) »
  • Park JY  et al. From peripheral to central: the role of ERK signaling pathway in acupuncture analgesia. J Pain 15:535-49 (2014). IF ; Mouse . Read more (PubMed: 24524846) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"