Anti-Cytokeratin 7 antibody [SP52] (ab119697)

Overview

  • Product nameAnti-Cytokeratin 7 antibody [SP52]
    See all Cytokeratin 7 primary antibodies
  • Description
    Rabbit monoclonal [SP52] to Cytokeratin 7
  • Tested applicationsSuitable for: IHC-P, WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to C-terminus of Human Cytokeratin 7.

  • Positive control
    • HeLa cell lysate, Human Breast or ovarian carcinoma tissues

Properties

Applications

Our Abpromise guarantee covers the use of ab119697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/25. Detects a band of approximately 54 kDa (predicted molecular weight: 51 kDa).
Flow Cyt 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • FunctionBlocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
  • Tissue specificityExpressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Post-translational
    modifications
    Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CK 7 antibody
    • CK-7 antibody
    • CK7 antibody
    • Cytokeratin 7 antibody
    • Cytokeratin-7 antibody
    • D15Wsu77e antibody
    • K2C7 antibody
    • K2C7_HUMAN antibody
    • K7 antibody
    • Keratin 7 antibody
    • Keratin 7, type II antibody
    • Keratin type II cytoskeletal 7 antibody
    • Keratin, 55K type II cytoskeletal antibody
    • Keratin, simple epithelial antibody
    • Keratin, simple epithelial type I, K7 antibody
    • Keratin, type II cytoskeletal 7 antibody
    • Keratin-7 antibody
    • Krt2-7 antibody
    • KRT7 antibody
    • MGC11625 antibody
    • MGC129731 antibody
    • MGC3625 antibody
    • Sarcolectin antibody
    • SCL antibody
    • Type II mesothelial keratin K7 antibody
    • Type-II keratin Kb7 antibody
    see all

Anti-Cytokeratin 7 antibody [SP52] images

  • Flow cytometric analysis of rabbit anti-Cytokeratin 7 (SP52) antibody ab119697 (1/100) in HeLa cells (green) compare to negative control of rabbit IgG (blue).

  • Anti-Cytokeratin 7 antibody [SP52] (ab119697) at 1/25 dilution + HeLa cell lysate

    Predicted band size : 51 kDa
  • Human breast carcinoma tissue stained with ab119697 at a dilution of 1/100.

References for Anti-Cytokeratin 7 antibody [SP52] (ab119697)

ab119697 has not yet been referenced specifically in any publications.

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