Anti-Cytomegalovirus AD169 antibody (ab31991)

Overview

  • Product nameAnti-Cytomegalovirus AD169 antibody
    See all Cytomegalovirus AD169 primary antibodies
  • Description
    Goat polyclonal to Cytomegalovirus AD169
  • Specificityab31991 recognizes Cytomegalovirus, Strain AD 169. It shows predominant reactivity to glycoprotein B (gB), and does not crossreact with HSV and V2V by Immunofluorescence. Negative vs Hep2 cells and human fibroblasts by Indirect Immunofluorescence.
  • Tested applicationsSuitable for: ELISA, Conjugation, ICC, WB, ICC/IFmore details
  • Species reactivity
    Cytomegalovirus, Strain AD 169.
  • Immunogen

    Purified virons of Cytomegalovirus, Strain AD 169.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.1% Sodium Azide.
    Constituents: PBS.
  • Concentration information loading...
  • Purity>95% by SDS-PAGE
  • Purification notesab31991 was purified by sodium sulfate precipitation and ion exchange chromatography (> 95%).
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab31991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Conjugation
ICC
WB
ICC/IF
  • Application notesConjugation: Use at an assay dependent dilution.
    ELISA: Use at an assay dependent dilution.
    ICC: Use at an assay dependent dilution.
    IF (indirect): 1/2000.
    WB: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceCytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. Cytomegalovirus strain AD169 is a laboratory-adapted strain and appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.
    • Alternative names
      • HCMV antibody
      • HHV5 antibody
      • Human Herpesvirus 5 antibody
      • UL55 (strain AD169) antibody

    References for Anti-Cytomegalovirus AD169 antibody (ab31991)

    ab31991 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"