Overview

  • Product nameAnti-D-Dimer antibody [DD4] (HRP)
    See all D-Dimer primary antibodies
  • Description
    Mouse monoclonal [DD4] to D-Dimer (HRP)
  • ConjugationHRP
  • Specificityab10054 is specific for D-dimer and high molecular weight fibrin degradation products. Low cross-reaction with D-monomer, cross-reaction with fibrinogen. Good for detection MAb in two-step sandwich IA.
  • Tested applicationsSuitable for: Sandwich ELISA, ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    This clone has been derived from hybridization of Sp 2/0 myeloma cells with spleen cells of Balb/c mice immunized with homogenized fibrin clot.

  • General notesConcentration varies from lot to lot and can be provided on request.

Properties

Applications

Our Abpromise guarantee covers the use of ab10054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [DD1] to D-Dimer (ab10050) and Mouse monoclonal [DD2] to D-Dimer (ab10052) and Mouse monoclonal [DD3] to D-Dimer (ab10053). Can be used as Detection antibody. Recommended for D-Dimer detection in Human Plasma.
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [DD1] to D-Dimer (ab10050) and Mouse monoclonal [DD2] to D-Dimer (ab10052) and Mouse monoclonal [DD3] to D-Dimer (ab10053).
WB Use at an assay dependent dilution.

Target

  • RelevanceA fibrin degradation fragment or product that is produced by the action of plasmin on fibrin in the clot dissolution process.
  • Alternative names
    • D Dimer antibody

References for Anti-D-Dimer antibody [DD4] (HRP) (ab10054)

This product has been referenced in:
  • Gamella M  et al. Amperometric Magnetoimmunosensors for Direct Determination of D-Dimer in Human Serum Electroanalysis 24:2235-2243 (2012). Read more (PubMed: ) »
  • Avery JW  et al. Maternal malaria induces a procoagulant and antifibrinolytic state that is embryotoxic but responsive to anticoagulant therapy. PLoS One 7:e31090 (2012). Read more (PubMed: 22347435) »

See all 3 Publications for this product

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Respecto a la especificidad de los anticuerpos anti-D-Dimer disponibles en el catálogo, los clones DD1, DD2 y DD3 son específicos para D Dimer y otros productos de pesos molecular elevados producto de la degradación de la...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"