Overview

  • Product name
  • Description
    Rabbit polyclonal to D4 GDI
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human).

  • Positive control
    • Placenta and tonsil.

Properties

Applications

Our Abpromise guarantee covers the use of ab15198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notes
    IHC-P: 1/100 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
    WB: Use at a concentration of 1 µg/ml for 2hours. Predicted molecular weight: 23 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
    • Tissue specificity
      Detected in bone marrow, thymus and spleen.
    • Sequence similarities
      Belongs to the Rho GDI family.
    • Cellular localization
      Cytoplasm, cytosol.
    • Information by UniProt
    • Database links
    • Alternative names
      • Arhgdib antibody
      • D4 antibody
      • D4 GDP dissociation inhibitor antibody
      • GDIA 2 antibody
      • GDIA2 antibody
      • GDID 4 antibody
      • GDID4 antibody
      • GDIR2_HUMAN antibody
      • GDP dissociation inhibitor D4 antibody
      • LY GDI antibody
      • Ly-GDI antibody
      • LYGDI antibody
      • MGC108926 antibody
      • RAP1GN1 antibody
      • Rho GDI 2 antibody
      • Rho GDI beta antibody
      • Rho GDI2 antibody
      • Rho GDP dissociation inhibitor (GDI) beta antibody
      • Rho GDP dissociation inhibitor 2 antibody
      • Rho GDP dissociation inhibitor beta antibody
      • Rho GDP-dissociation inhibitor 2 antibody
      • Rho-GDI beta antibody
      • RhoGDI2 antibody
      see all

    Images

    • ab15198 staining D4 GDI in human tonsil by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    • Anti-D4 GDI antibody (ab15198) at 1/25 dilution + Jurkat cell lysate

      Predicted band size : 23 kDa
      Observed band size : 23 kDa

    References

    This product has been referenced in:
    • Mercey O  et al. Characterizing isomiR variants within the microRNA-34/449 family. FEBS Lett 591:693-705 (2017). WB . Read more (PubMed: 28192603) »
    • Lai MC  et al. Prognostic value of Rho GDP dissociation inhibitors in patients with hepatocellular carcinoma following liver transplantation. Oncol Lett 14:1395-1402 (2017). Read more (PubMed: 28789355) »

    See all 5 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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