Overview

  • Product name
  • Description
    Rabbit polyclonal to Dab1
  • Tested applications
    Suitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    The antiserum was produced against synthesized non-phosphopeptide derived from human Dab1 around the phosphorylation site of tyrosine 232 (G-V-YP-D-V).

  • Positive control
    • Human breast carcinoma

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab47483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
ELISA
  • Application notes
    ELISA: 1/10000.
    IHC-P: 1/50 - 1/100.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Adapter molecule functioning in neural development. May regulate SIAH1 activity.
    • Sequence similarities
      Contains 1 PID domain.
    • Domain
      The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
    • Post-translational
      modifications
      Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
    • Information by UniProt
    • Database links
    • Alternative names
      • Dab 1 antibody
      • Dab reelin signal transducer 1 antibody
      • Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
      • Dab1 antibody
      • DAB1_HUMAN antibody
      • Disabled homolog 1 antibody
      • Disabled homolog 1 Drosophila antibody
      • Scm antibody
      • Scr antibody
      • Scrambler antibody
      • Yot antibody
      • Yotari antibody
      see all

    Anti-Dab1 antibody images

    • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab47483. Left hand image untreated ; right hand image treated with peptide

    References for Anti-Dab1 antibody (ab47483)

    ab47483 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab47483.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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