Overview

  • Product nameAnti-Dab1 antibody [EP2248Y]
    See all Dab1 primary antibodies
  • Description
    Rabbit monoclonal [EP2248Y] to Dab1
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    A synthetic peptide corresponding to residues surrounding serine 491 of human Dab1.

  • Positive control
    • Rat brain lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Human: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab68461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/1000 - 1/2000. Detects a band of approximately 70 kDa (predicted molecular weight: 67 kDa).

    Is unsuitable for Flow Cyt, ICC/IF, IHC-P or IP.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAdapter molecule functioning in neural development. May regulate SIAH1 activity.
    • Sequence similaritiesContains 1 PID domain.
    • DomainThe PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
    • Post-translational
      modifications
      Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
    • Information by UniProt
    • Database links
    • Alternative names
      • Dab 1 antibody
      • Dab reelin signal transducer 1 antibody
      • Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
      • Dab1 antibody
      • DAB1_HUMAN antibody
      • Disabled homolog 1 antibody
      • Disabled homolog 1 Drosophila antibody
      • Scm antibody
      • Scr antibody
      • Scrambler antibody
      • Yot antibody
      • Yotari antibody
      see all

    Anti-Dab1 antibody [EP2248Y] images

    • Anti-Dab1 antibody [EP2248Y] (ab68461) at 1/2000 dilution + Rat brain lysate at 10 µg

      Secondary
      HRP conjugated Goat anti Rabbit. at 1/2000 dilution

      Predicted band size : 67 kDa
      Observed band size : 70 kDa (why is the actual band size different from the predicted?)

    References for Anti-Dab1 antibody [EP2248Y] (ab68461)

    ab68461 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab68461.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"