Recombinant
RabMAb

Anti-Dab1 antibody [EP2248Y] (ab68461)

Overview

  • Product name
    Anti-Dab1 antibody [EP2248Y]
    See all Dab1 primary antibodies
  • Description
    Rabbit monoclonal [EP2248Y] to Dab1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    A synthetic peptide corresponding to residues surrounding serine 491 of human Dab1.

  • Positive control
    • Rat brain lysate.
  • General notes

    Human: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab68461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: 1/1000 - 1/2000. Detects a band of approximately 70 kDa (predicted molecular weight: 67 kDa).

    Is unsuitable for Flow Cyt, ICC/IF, IHC-P or IP.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Adapter molecule functioning in neural development. May regulate SIAH1 activity.
    • Sequence similarities
      Contains 1 PID domain.
    • Domain
      The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
    • Post-translational
      modifications
      Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
    • Information by UniProt
    • Database links
    • Alternative names
      • Dab 1 antibody
      • Dab reelin signal transducer 1 antibody
      • Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
      • Dab1 antibody
      • DAB1_HUMAN antibody
      • Disabled homolog 1 antibody
      • Disabled homolog 1 Drosophila antibody
      • Scm antibody
      • Scr antibody
      • Scrambler antibody
      • Yot antibody
      • Yotari antibody
      see all

    Images

    • Anti-Dab1 antibody [EP2248Y] (ab68461) at 1/2000 dilution + Rat brain lysate at 10 µg

      Secondary
      HRP conjugated Goat anti Rabbit. at 1/2000 dilution

      Predicted band size: 67 kDa
      Observed band size: 70 kDa (why is the actual band size different from the predicted?)

    References

    ab68461 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab68461.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up