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Rabbit polyclonal to Dab1 (phospho Y232)
This antibody detects endogenous levels of Dab1 only when phosphorylated at tyrosine 232.
Predicted to work with:
Synthesized phosphopeptide derived from human Dab1 around the phosphorylation site of tyrosine 232 (G-V-Y
Extracts from LOVO cells.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
Concentration information loading...
Immunogen affinity purified
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
Adapter molecule functioning in neural development. May regulate SIAH1 activity.
Contains 1 PID domain.
The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
Information by UniProt
Dab 1 antibody
Dab reelin signal transducer 1 antibody
Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
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