Anti-Dact1 / Dapper homolog 1 antibody (ab116342)

Overview

  • Product nameAnti-Dact1 / Dapper homolog 1 antibody
    See all Dact1 / Dapper homolog 1 primary antibodies
  • Description
    Rabbit polyclonal to Dact1 / Dapper homolog 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 343-392 (LSLVQKKTHP VRTNKPRTSV NADPTKGLLR NGSVCVRAPG GVSQGNSVNL) of Human Dact1/ Dapper homolog 1 (NP_057735).

  • Positive control
    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116342 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 90 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionPositively regulates DVL2-mediated signaling pathways during development. Binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
  • Sequence similaritiesBelongs to the dapper family.
  • DomainThe C-terminal PDZ-binding motif mediates interaction with the PDZ domains of DSH (Dishevelled) family proteins.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dact antibody
    • dact1 antibody
    • DACT1_HUMAN antibody
    • Dapper antagonist of beta catenin homolog 1 antibody
    • Dapper antagonist of catenin 1 antibody
    • Dapper antibody
    • Dapper homolog 1 antibody
    • DAPPER1 antibody
    • Dpr antibody
    • Dpr1 antibody
    • Frd antibody
    • Frodo antibody
    • hDPR1 antibody
    • Hepatocellular carcinoma novel gene 3 protein antibody
    • Heptacellular carcinoma novel gene 3 antibody
    • HNG3 antibody
    • MTNG3 antibody
    • Thyex3 antibody
    see all

Anti-Dact1 / Dapper homolog 1 antibody images

  • Anti-Dact1 / Dapper homolog 1 antibody (ab116342) at 1 µg/ml + 293T cell lysate at 10 µg

    Predicted band size : 90 kDa

References for Anti-Dact1 / Dapper homolog 1 antibody (ab116342)

ab116342 has not yet been referenced specifically in any publications.

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