Overview

  • Product nameDaidzein
  • Description
    Phytoestrogen
  • Biological descriptionPhytoestrogen, and soy isoflavone. Analog of genistein (ab120112). Various biological actions, including a weak estrogenic / antiestrogenic effect by binding to the nuclear estrogen receptor.
  • Purity> 99%

Properties

    Associated products

    Daidzein images

    • ab47489 staining Bcl2 MCF7 cells treated with diadzein (ab120391), by ICC/IF. Decrease in Bcl2 expression correlates with increased concentration of diadzein, as described in literature.
      The cells were incubated at 37°C for 6h in media containing different concentrations of ab120391 (diadzein) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab47489 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.

    References for Daidzein (ab120391)

    This product has been referenced in:
    • Hwang CS  et al. Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration. J Steroid Biochem Mol Biol 101:246-53 (2006). Read more (PubMed: 16965913) »
    • Kurzer MS & Xu X Dietary phytoestrogens. Annu Rev Nutr 17:353-81 (1997). Read more (PubMed: 9240932) »

    See 1 Publication for this product

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