The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250. Detects a band of approximately 160 kDa.
FunctionCalcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. Contains 10 ANK repeats. Contains 1 death domain. Contains 1 protein kinase domain.
Post-translational modificationsUbiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.
Cellular localizationCytoplasm. Colocalizes with the actin filament system.