Overview

  • Product nameAnti-DAP5 antibody
    See all DAP5 primary antibodies
  • Description
    Rabbit polyclonal to DAP5
  • Tested applicationsSuitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus)
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 125-175 of Human DAP5 (NP_001409.1).

  • Positive control
    • Human Non-Small Cell Lung Cancer and Human Ovarian Carcinoma tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab117804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.
ICC/IF 1/100 - 1/500.

Target

  • FunctionAppears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
  • Tissue specificityUbiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.
  • Sequence similaritiesBelongs to the eIF4G family.
    Contains 1 MI domain.
    Contains 1 MIF4G domain.
    Contains 1 W2 domain.
  • Post-translational
    modifications
    Phosphorylation; hyperphosphorylated during mitosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • DAP-5 antibody
    • Death associated protein 5 antibody
    • Death-associated protein 5 antibody
    • eIF-4-gamma 2 antibody
    • eIF-4G 2 antibody
    • eIF4G 2 antibody
    • EIF4G2 antibody
    • Eukaryotic translation initiation factor 4 gamma 2 antibody
    • IF4G2_HUMAN antibody
    • Nat1 antibody
    • Novel APOBEC-1 target 1 antibody
    • p97 antibody
    • Translation repressor NAT1 antibody
    • Translation repressor NAT1 antibody
    see all

Anti-DAP5 antibody images

  • ab117804 at 1/250 dilution staining DAP5 in Formalin-fixed, Paraffin-embedded Human ovarian carcinoma tissue by Immunohistochemistry.
    Detection: DAB staining.
  • ab117804 at 1/100 dilution staining DAP5 in Formalin-fixed Paraffin-embedded Human ovarian carcinoma tissue by Immunofluorescence. Detection:Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1/100.

References for Anti-DAP5 antibody (ab117804)

ab117804 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"