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Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Dissociation constant (K
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/10000 - 1/50000. Predicted molecular weight: 77 kDa.
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Contains 2 BRCT domains.
Contains 1 DBF4-type zinc finger.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
Activator of S phase kinase antibody
Anti-DBF4 antibody [EPR5635] images
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