Overview

  • Product name
  • Description
    Rabbit polyclonal to DBX1
  • Specificity
    ab156283 is predicted to not cross-react with other DBX protein family members.
  • Tested applications
    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to 15 internal sequence amino acids of Human DBX1 (NP_001025036).

  • Positive control
    • Mouse kidney tissue lysate; Human kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab156283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • Relevance
    Dbx1 homeodomain transcription factor is expressed in progenitors at the boundary between the dorsal and ventral plates of the caudal neural tube, from which postmitotic cells migrate tangentially to their final destination. Dbx1 is implicated in patterning the central nervous system during embryogenesis. Cell fate allocation and cell diversity are determined at very early stages in progenitor cells at precise coordinates along the dorsoventral and anteroposterior axis. In the spinal cord, the spatially restricted expression of Dbx1 in progenitors is critical in establishing interneuron cell fates and helps coordinate diverse phenotypic features. In the telencephalon, Dbx1 is expressed in restricted progenitor domains at the borders of the developing pallium.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • dbx antibody
    • Developing brain homeobox 1 antibody
    • Developing brain homeobox protein 1 antibody
    • Homeobox protein DBX1 antibody

Images

  • Immunofluorescence of DBX1 in Human kidney tissue with ab156283 at 20 ug/mL.
  • Lane 1 : Anti-DBX1 antibody (ab156283) at 1 µg/ml
    Lane 2 : Anti-DBX1 antibody (ab156283) at 2 µg/ml

    Lane 1 : Mouse kidney tissue lysate
    Lane 2 : Mouse kidney tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 37 kDa
  • Immunohistochemical analysis of Paraffin-embedded Human kidney tissue labeling DBX1 with ab156283 at 2.5 µg/ml.

References

ab156283 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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