Overview

  • Product name
  • Description
    Rabbit polyclonal to DCAMKL2
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 14 amino acid peptide near the carboxy terminus of Human DCAMKL2 (NP_001035350).

  • Positive control
    • Rat brain tissue and tissue lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    ab106639 is purified by affinity chromatography via a peptide column.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 84 kDa.

Target

  • Function
    Protein kinase with a significantly reduced Ca2+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 2 doublecortin domains.
    Contains 1 protein kinase domain.
  • Domain
    The doublecortin domains are involved in the colocalization with microtubules.
  • Cellular localization
    Cytoplasm > cytoskeleton. Colocalizes with microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • CaMK-like CREB regulatory kinase 2 antibody
    • CL2 antibody
    • CLICK-II antibody
    • CLICK2 antibody
    • DCAMK L2 antibody
    • DCAMKL 2 antibody
    • DCDC 3 antibody
    • DCDC 3B antibody
    • DCDC3 antibody
    • DCDC3B antibody
    • DCK 2 antibody
    • DCK2 antibody
    • DCLK 2 antibody
    • Dclk2 antibody
    • DCLK2_HUMAN antibody
    • DKFZp761I032 antibody
    • Doublecortin and CaM kinase like 2 antibody
    • Doublecortin domain-containing protein 3B antibody
    • Doublecortin like and CAM kinase like 2 antibody
    • Doublecortin like kinase 2 antibody
    • Doublecortin-like and CAM kinase-like 2 antibody
    • Doublecortin-like kinase 2 antibody
    • MGC45428 antibody
    • Serine/threonine protein kinase DCLK2 antibody
    • Serine/threonine-protein kinase DCLK2 antibody
    see all

Images



  • Predicted band size : 84 kDa
    Western Blot of rat brain tissue lysate labeling DCAMKL2 with Anti-DCAMKL2 antibody (ab106639) at (1) 1 and (2) 2µg/ml.
  • Lane 1 : Anti-DCAMKL2 antibody (ab106639) at 1 µg/ml
    Lane 2 : Anti-DCAMKL2 antibody (ab106639) at 2 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 84 kDa
  • ab106639 at 5µg/ml, staining DCAMKL2 in Rat brain, using Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

References

ab106639 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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