Anti-DCAMKL2 antibody - Aminoterminal end (ab71456)

Overview

  • Product name
    Anti-DCAMKL2 antibody - Aminoterminal end
    See all DCAMKL2 primary antibodies
  • Description
    Rabbit polyclonal to DCAMKL2 - Aminoterminal end
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Positive control
    • HeLa cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Ammonium Sulphate Precipitation
  • Purification notes
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab71456 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 84 kDa (predicted molecular weight: 84 kDa).

Target

  • Function
    Protein kinase with a significantly reduced Ca2+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 2 doublecortin domains.
    Contains 1 protein kinase domain.
  • Domain
    The doublecortin domains are involved in the colocalization with microtubules.
  • Cellular localization
    Cytoplasm > cytoskeleton. Colocalizes with microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • CaMK-like CREB regulatory kinase 2 antibody
    • CL2 antibody
    • CLICK-II antibody
    • CLICK2 antibody
    • DCAMK L2 antibody
    • DCAMKL 2 antibody
    • DCDC 3 antibody
    • DCDC 3B antibody
    • DCDC3 antibody
    • DCDC3B antibody
    • DCK 2 antibody
    • DCK2 antibody
    • DCLK 2 antibody
    • Dclk2 antibody
    • DCLK2_HUMAN antibody
    • DKFZp761I032 antibody
    • Doublecortin and CaM kinase like 2 antibody
    • Doublecortin domain-containing protein 3B antibody
    • Doublecortin like and CAM kinase like 2 antibody
    • Doublecortin like kinase 2 antibody
    • Doublecortin-like and CAM kinase-like 2 antibody
    • Doublecortin-like kinase 2 antibody
    • MGC45428 antibody
    • Serine/threonine protein kinase DCLK2 antibody
    • Serine/threonine-protein kinase DCLK2 antibody
    see all

Images

  • Anti-DCAMKL2 antibody - Aminoterminal end (ab71456) at 1/60 dilution + HeLa cell line lysate at 12.5 µg

    Predicted band size : 84 kDa
    Observed band size : 84 kDa
    Additional bands at : 56 kDa. We are unsure as to the identity of these extra bands.

References

ab71456 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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