Overview

  • Product nameAnti-DCDC2 antibody
    See all DCDC2 primary antibodies
  • Description
    Rabbit polyclonal to DCDC2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 251-300 (KGSGNDRHSK STVGSSDNSS PQPLKRKGKK EDVNSEKLTK LKQNVKLKNS) of Human DCDC2 (NP_057440).

  • Positive control
    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab104348 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay be involved in neuronal migration during development of the cerebral neocortex.
  • Tissue specificityUbiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus.
  • Involvement in diseaseDefects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability.
  • Sequence similaritiesContains 2 doublecortin domains.
  • Information by UniProt
  • Database links
  • Alternative names
    • DCDC2 antibody
    • DCDC2_HUMAN antibody
    • DCDC2A antibody
    • Doublecortin domain containing 2 antibody
    • Doublecortin domain-containing protein 2 antibody
    • Protein RU2S antibody
    • RU2 antibody
    • RU2S antibody
    see all

Anti-DCDC2 antibody images

  • Anti-DCDC2 antibody (ab104348) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 53 kDa

References for Anti-DCDC2 antibody (ab104348)

ab104348 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"