Overview

  • Product name
  • Description
    Goat polyclonal to DCDC2
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Synthetic peptide:

    C-PQPLKRKGKKDSN

    , corresponding to internal sequence amino acids 271-283 of Mouse DCDC2

  • Positive control
    • Mouse Brain lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab53549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: Peptide ELISA: Antibody detection limit dilution 1/32000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 41 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May be involved in neuronal migration during development of the cerebral neocortex.
    • Tissue specificity
      Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus.
    • Involvement in disease
      Defects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability.
    • Sequence similarities
      Contains 2 doublecortin domains.
    • Information by UniProt
    • Database links
    • Alternative names
      • DCDC 2 antibody
      • DCDC2 antibody
      • DCDC2_HUMAN antibody
      • DCDC2A antibody
      • Doublecortin domain containing 2 antibody
      • doublecortin domain containing protein 2 antibody
      • Doublecortin domain-containing protein 2 antibody
      • HGNC:18141 antibody
      • KIAA1154 antibody
      • Protein RU2S antibody
      • RU 2 antibody
      • RU2 antibody
      • RU2S antibody
      • RU2S protein antibody
      see all

    Images

    References

    ab53549 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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