Overview

  • Product nameAnti-DcR1 antibody [B-H47]
    See all DcR1 primary antibodies
  • Description
    Mouse monoclonal [B-H47] to DcR1
  • SpecificityRecognises the 75.90kDa protein
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human DcR1/Fc chimera

Properties

Applications

Our Abpromise guarantee covers the use of ab59507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 65 kDa.

Target

  • RelevanceDcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
  • Cellular localizationCell Membrane and Cytoplasmic
  • Database links
  • Alternative names
    • Antagonist decoy receptor for TRAIL/Apo 2L antibody
    • CD263 antibody
    • Cytotoxic TRAIL receptor 3 antibody
    • DCR1 antibody
    • DCR1 TNFR antibody
    • Decoy Receptor 1 antibody
    • Decoy TRAIL receptor without death domain antibody
    • LIT antibody
    • Lymphocyte inhibitor of TRAIL antibody
    • MGC149501 antibody
    • MGC149502 antibody
    • TNF related apoptosis inducing ligand receptor 3 antibody
    • TNF-re ated apoptosis inducing ligand receptor 3 antibody
    • TNFRSF10C antibody
    • TRAIL R3 antibody
    • TRAIL receptor 3 antibody
    • TRAILR3 antibody
    • TRID antibody
    • Tumor necrosis factor receptor superfamily member 10C antibody
    • Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain antibody
    see all

References for Anti-DcR1 antibody [B-H47] (ab59507)

ab59507 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"