Overview

  • Product nameAnti-DcR2 antibody
    See all DcR2 primary antibodies
  • Description
    Rabbit polyclonal to DcR2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within C terminal amino acids 253-283 of Human DcR2 (NP_003831.20).

  • Positive control
    • CEM cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab116450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.

Target

  • FunctionReceptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
  • Tissue specificityWidely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
  • Sequence similaritiesContains 1 death domain.
    Contains 3 TNFR-Cys repeats.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 264 antibody
    • CD264 antibody
    • DcR 2 antibody
    • DcR2 antibody
    • Decoy receptor 2 antibody
    • Decoy with truncated death domain antibody
    • OTTHUMP00000123528 antibody
    • TNF receptor related receptor for TRAIL antibody
    • TNF related apoptosis inducing ligand receptor 4 antibody
    • TNF-related apoptosis-inducing ligand receptor 4 antibody
    • TNFRSF 10D antibody
    • TNFRSF10D antibody
    • TR10D_HUMAN antibody
    • TRAIL R4 antibody
    • TRAIL receptor 4 antibody
    • TRAIL receptor with a truncated death domain antibody
    • TRAIL-R4 antibody
    • TRAILR4 antibody
    • TRUNDD antibody
    • Tumor necrosis factor receptor superfamily member 10D antibody
    • Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain antibody
    see all

Anti-DcR2 antibody images

  • Anti-DcR2 antibody (ab116450) at 1/100 dilution + CEM cell line lysates at 35 µg

    Predicted band size : 42 kDa

References for Anti-DcR2 antibody (ab116450)

ab116450 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"