Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab8379 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • CD 264
    • CD264
    • DcR 2
    • DcR2
    • Decoy receptor 2
    • Decoy with truncated death domain
    • OTTHUMP00000123528
    • TNF receptor related receptor for TRAIL
    • TNF related apoptosis inducing ligand receptor 4
    • TNF-related apoptosis-inducing ligand receptor 4
    • TNFRSF 10D
    • TNFRSF10D
    • TR10D_HUMAN
    • TRAIL R4
    • TRAIL receptor 4
    • TRAIL receptor with a truncated death domain
    • TRAIL-R4
    • TRAILR4
    • TRUNDD
    • Tumor necrosis factor receptor superfamily member 10D
    • Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
    see all
  • FunctionReceptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
  • Tissue specificityWidely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
  • Sequence similaritiesContains 1 death domain.
    Contains 3 TNFR-Cys repeats.
  • Cellular localizationMembrane.
  • Information by UniProt

References for DcR2 peptide (ab8379)

ab8379 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab8379.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"