Overview

  • Product nameAnti-DcR3 antibody
    See all DcR3 primary antibodies
  • Description
    Rabbit polyclonal to DcR3
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Peptide corresponding to amino acids 31 to 46 ofhuman DcR3 precursor (1,2).

  • Positive control
    • Tissue lysate of human heart, brain or kidney

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab8405 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 1 µg/ml.
WB 1/500 - 1/1000. Detects a band of approximately 33 kDa.Can be blocked with DcR3 peptide (ab8437).

Target

  • FunctionDecoy receptor for the cytotoxic ligands TNFS14/LIGHT and TNFSF6/FASL. Protects against apoptosis.
  • Tissue specificityDetected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
  • Sequence similaritiesContains 4 TNFR-Cys repeats.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • DcR3 antibody
    • Decoy receptor 3 antibody
    • Decoy receptor for Fas ligand antibody
    • DJ583P15.1.1 antibody
    • M68 antibody
    • M68E antibody
    • OTTHUMP00000031583 antibody
    • TNF6B_HUMAN antibody
    • TNFRSF6B antibody
    • TR6 antibody
    • Tumor necrosis factor receptor superfamily member 6B antibody
    • Tumor necrosis factor receptor superfamily member 6b decoy antibody
    • UNQ186/PRO212 antibody
    see all

Anti-DcR3 antibody images

  • All lanes : Anti-DcR3 antibody (ab8405) at 1/500 dilution

    Lane 1 : Human heart tissue lysate
    Lane 2 : Human brain tissue lysate
    Lane 3 : Human kidney tissue lysate


    Observed band size : 33 kDa (why is the actual band size different from the predicted?)
  • ab8405 at 1µg/ml staining DcR3 in human heart tissue by IHC 

References for Anti-DcR3 antibody (ab8405)

ab8405 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your e-mail and your patience. I have reviewed your protocol as well as the correspondence you have had with my colleague Tom and I understand that you have had problems with ab8405 after an immunoprecipitation step or with a simple west...

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