Overview

  • Product name
    Anti-DCTN4 antibody [2244C3a]
    See all DCTN4 primary antibodies
  • Description
    Mouse monoclonal [2244C3a] to DCTN4
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment corresponding to an internal region of Human DCTN4

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    2244C3a
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 52 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
  • Sequence similarities
    Belongs to the dynactin subunit 4 family.
  • Cellular localization
    Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution, suggesting that this polypeptide may be targeted to the nucleus at very high expression levels.
  • Information by UniProt
  • Database links
  • Alternative names
    • DCTN 4 antibody
    • Dctn4 antibody
    • DCTN4_HUMAN antibody
    • Dynactin 4 (p62) antibody
    • Dynactin 4 antibody
    • Dynactin p62 subunit antibody
    • Dynactin subunit 4 antibody
    • Dynactin subunit p62 antibody
    • Dynactin4 antibody
    • p62 antibody
    see all

Images

  • Anti-DCTN4 antibody [2244C3a] (ab84861) + Immunogen (recombinant fragment of Human protein)

    Predicted band size : 52 kDa

References

ab84861 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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