Overview

  • Product nameAnti-DCTN4 antibody
    See all DCTN4 primary antibodies
  • Description
    Rabbit polyclonal to DCTN4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 of Human DCTN4 (NP_057305).

  • Positive control
    • Human fetal muscle lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Optimal concentration of antibody depends the protein level in a given sample. Our recommended concentrations are the starting point for general use. Customers are advised have to do a series of titration tests to determine optimal concentration. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCould have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
  • Sequence similaritiesBelongs to the dynactin subunit 4 family.
  • Cellular localizationCytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution, suggesting that this polypeptide may be targeted to the nucleus at very high expression levels.
  • Information by UniProt
  • Database links
  • Alternative names
    • DCTN 4 antibody
    • Dctn4 antibody
    • DCTN4_HUMAN antibody
    • Dynactin 4 (p62) antibody
    • Dynactin 4 antibody
    • Dynactin p62 subunit antibody
    • Dynactin subunit 4 antibody
    • Dynactin subunit p62 antibody
    • Dynactin4 antibody
    • p62 antibody
    see all

Anti-DCTN4 antibody images



  • Predicted band size : 52 kDa
    Western blot analysis of Human fetal brain tissue lysate labeling DCTN4 with ab98098 at 1.0µg/ml.
  • Anti-DCTN4 antibody (ab98098) at 1 µg/ml + Human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 52 kDa
    Gel concentration: 12%

References for Anti-DCTN4 antibody (ab98098)

ab98098 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"