Overview

  • Product nameAnti-DCXR antibody
    See all DCXR primary antibodies
  • Description
    Rabbit polyclonal to DCXR
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cynomolgus Monkey
  • Immunogen

    VMTSMGQATW SDPHKAKTML NRIPLGKFAE VEHVVNAILF LLSDRSGMTT GSTLPVEGGF WAC, corresponding to amino acids 182-244 of Human DCXR (NP_057370).

  • Positive control
    • HepG2 whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab96778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 26 kDa.

Target

  • FunctionCatalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • Tissue specificityHighly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • Involvement in diseaseNote=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localizationMembrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
  • Information by UniProt
  • Database links
  • Alternative names
    • Carbonyl reductase 2 antibody
    • Carbonyl reductase II antibody
    • DCR antibody
    • Dcxr antibody
    • DCXR_HUMAN antibody
    • Dicarbonyl L xylulose reductase antibody
    • Dicarbonyl/ L xylulose reductase antibody
    • Dicarbonyl/L-xylulose reductase antibody
    • HCR2 antibody
    • HCRII antibody
    • Human carbonyl reductase 2 antibody
    • kiDCR antibody
    • Kidney dicarbonyl reductase antibody
    • L xylulose reductase antibody
    • L-xylulose reductase antibody
    • P34H antibody
    • PNTSU antibody
    • SDR20C1 antibody
    • Short chain dehydrogenase/reductase family 20C member 1 antibody
    • Sperm surface protein P34H antibody
    • XR antibody
    see all

Anti-DCXR antibody images

  • Anti-DCXR antibody (ab96778) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 26 kDa

References for Anti-DCXR antibody (ab96778)

ab96778 has not yet been referenced specifically in any publications.

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