Overview

  • Product nameAnti-DDIT3 antibody
    See all DDIT3 primary antibodies
  • Description
    Rabbit polyclonal to DDIT3
  • Tested applicationsSuitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Xenopus laevis
  • Immunogen

    Synthetic peptide:

    KEATRRALIDRMVNLHQA

    conjugated to KLH, corresponding to amino acids 153-169 of Human DDIT3 (with added N-terminal K).

  • Positive control
    • Whole extract of growth arrested rat PC 12 pheochromocytoma cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab10444 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution. PubMed: 20683254
WB 1/250. Detects a band of approximately 29 kDa (predicted molecular weight: 20 kDa).

Target

  • FunctionInhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA.
  • Involvement in diseaseNote=A chromosomal aberration involving DDIT3 is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with FUS.
  • Sequence similaritiesBelongs to the bZIP family.
    Contains 1 bZIP domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • C/EBP homologous protein antibody
    • C/EBP Homology Protein antibody
    • C/EBP zeta antibody
    • C/EBP-homologous protein 10 antibody
    • C/EBP-homologous protein antibody
    • CCAAT/enhancer binding protein homologous protein antibody
    • CEBPZ antibody
    • CHOP 10 antibody
    • CHOP antibody
    • CHOP-10 antibody
    • CHOP10 antibody
    • DDIT 3 antibody
    • DDIT-3 antibody
    • Ddit3 antibody
    • DDIT3_HUMAN antibody
    • DNA Damage Inducible Transcript 3 antibody
    • DNA damage-inducible transcript 3 protein antibody
    • GADD 153 antibody
    • GADD153 antibody
    • Growth Arrest and DNA Damage Inducible Protein 153 antibody
    • Growth arrest and DNA damage inducible protein GADD153 antibody
    • Growth arrest and DNA damage-inducible protein GADD153 antibody
    • MGC4154 antibody
    see all

References for Anti-DDIT3 antibody (ab10444)

This product has been referenced in:
  • Galbes O  et al. N-acetylcysteine protects against bupivacaine-induced myotoxicity caused by oxidative and sarcoplasmic reticulum stress in human skeletal myotubes. Anesthesiology 113:560-9 (2010). WB, ICC/IF ; Human . Read more (PubMed: 20683254) »
  • Song J  et al. Severe burn-induced endoplasmic reticulum stress and hepatic damage in mice. Mol Med 15:316-20 (2009). WB ; Mouse . Read more (PubMed: 19603103) »

See all 2 Publications for this product

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"