Overview

  • Product nameAnti-DDIT4 antibody
    See all DDIT4 primary antibodies
  • Description
    Rabbit polyclonal to DDIT4
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to 12 amino acids from near the center of human DDIT4 (NP_061931)

  • Positive control
    • Human kidney tissue lysate; Mouse kidney tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab106356 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 25 kDa.

Target

  • FunctionInhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death.
  • Tissue specificityBroadly expressed, with lowest levels in brain, skeletal muscle and intestine. Up-regulated in substantia nigra neurons from Parkinson disease patients (at protein level).
  • Sequence similaritiesBelongs to the DDIT4 family.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • DDIT4 antibody
    • DDIT4_HUMAN antibody
    • Dig2 antibody
    • DNA damage inducible transcript 4 antibody
    • DNA damage inducible transcript 4 protein antibody
    • DNA damage-inducible transcript 4 protein antibody
    • FLJ20500 antibody
    • HIF 1 responsive protein RTP801 antibody
    • HIF 1 responsive RTP801 antibody
    • HIF-1 responsive protein RTP801 antibody
    • Protein regulated in development and DNA damage response 1 antibody
    • REDD-1 antibody
    • REDD1 antibody
    • RTP801 antibody
    see all

Anti-DDIT4 antibody images

  • Lane 1 : Anti-DDIT4 antibody (ab106356) at 0.5 µg/ml
    Lane 2 : Anti-DDIT4 antibody (ab106356) at 1 µg/ml

    Lane 1 : Human kidney tissue lysate
    Lane 2 : Human kidney tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 25 kDa
  • Immunohistochemistry detection of DDIT4 in paraffin embedded mouse kidney tissue section using ab106356 at 5 µg/ml.

References for Anti-DDIT4 antibody (ab106356)

This product has been referenced in:
  • Polioudakis D  et al. A Myc-microRNA network promotes exit from quiescence by suppressing the interferon response and cell-cycle arrest genes. Nucleic Acids Res 41:2239-54 (2013). Read more (PubMed: 23303785) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"