Overview

  • Product nameAnti-DDX21 antibody
    See all DDX21 primary antibodies
  • Description
    Rabbit polyclonal to DDX21
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Horse, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region between residues 725 and the C-terminal (residue 783) of Human DDX21 (NP_004719.2)

  • Positive control
    • Human larynx squamous cell carcinoma. Mouse squamous cell carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84394 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCan unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase). Functions as cofactor for JUN-activated transcription. Involved in rRNA processing.
    • Sequence similaritiesBelongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
      Contains 1 helicase ATP-binding domain.
      Contains 1 helicase C-terminal domain.
    • DomainThe two enzymatic activities reside in two separate domains, the helicase in the N-terminus and the foldase in the C-terminus.
      The 3 X 5 AA repeats seem to be critical for the RNA folding activity.
    • Cellular localizationNucleus > nucleolus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Ddx21 antibody
      • DDX21_HUMAN antibody
      • DEAD (Asp-Glu-Ala-Asp) box helicase 21 antibody
      • DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 antibody
      • DEAD box protein 21 antibody
      • EC 3.6.1.- antibody
      • Gu alpha antibody
      • Gu protein antibody
      • Gu-alpha antibody
      • GUA antibody
      • GURDB antibody
      • Nucleolar RNA helicase 2 antibody
      • Nucleolar RNA helicase Gu antibody
      • Nucleolar RNA helicase II antibody
      • RH II/Gu antibody
      • RH II/GuA antibody
      • RNA helicase II/Gu alpha antibody
      see all

    Anti-DDX21 antibody images

    • Detection of Human DDX21 by Immunohistochemistry.
      Sample: FFPE section of Human larynx squamous cell carcinoma.
      Antibody: ab84394 used at a dilution of 1/250.
      Detection: DAB.
    • Detection of Mouse DDX21 by Immunohistochemistry.
      Sample: FFPE section of Mouse squamous cell carcinoma.
      Antibody: ab84394 used at a dilution of 1/250.
      Detection: DAB.

    References for Anti-DDX21 antibody (ab84394)

    ab84394 has not yet been referenced specifically in any publications.

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"