Overview

  • Product name
  • Description
    Sheep polyclonal to Decorin
  • Specificity
    This antibody recognizes decorin.
  • Tested applications
    Suitable for: ELISAmore details
    Unsuitable for: IHC or WB
  • Species reactivity
    Reacts with: Chicken, Cow, Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide:

    IGPEVPDDRDFEPS

    conjugated to KLH, corresponding to amino acids 6-19 of Human Decorin (fragment 36-49 of the precursor molecule bone proteoglycan II).

Properties

Applications

Our Abpromise guarantee covers the use of ab31614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notes
    ELISA: 1/150 - 1/500.
    Coat with 1ug antigen per well. Use AP conjugated anti-sheep for detection.

    Is unsuitable for IHC and WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May affect the rate of fibrils formation.
    • Involvement in disease
      Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
    • Sequence similarities
      Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
      Contains 12 LRR (leucine-rich) repeats.
    • Post-translational
      modifications
      The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
    • Cellular localization
      Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • Bone proteoglycan II antibody
      • CSCD antibody
      • DCN antibody
      • DCN protein antibody
      • Decorin antibody
      • Decorin proteoglycan antibody
      • Dermatan sulphate proteoglycans II antibody
      • DKFZp686J19238 antibody
      • DSPG 2 antibody
      • DSPG2 antibody
      • PG 40 antibody
      • PG II antibody
      • PG S2 antibody
      • PG-S2 antibody
      • PG40 antibody
      • PGII antibody
      • PGS 2 antibody
      • PGS2 antibody
      • PGS2_HUMAN antibody
      • Proteoglycan core protein antibody
      • SLRR1B antibody
      • Small leucine rich protein 1B antibody
      see all

    References

    ab31614 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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