Overview

  • Product nameAnti-Decorin antibody
    See all Decorin primary antibodies
  • Description
    Sheep polyclonal to Decorin
  • SpecificityThis antibody reacts with Decorin.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Chicken, Cow, Human
    Predicted to work with: Mouse, Sheep, Rabbit, Horse, Dog, Xenopus laevis, Lizard, Rhesus monkey
  • Immunogen

    Synthetic peptide:

    CVYVRSAIQLGNYK

    (Human) conjugated to KLH

  • General notes


    The C terminal human sequence used to raise this antibody is also Bone Proteoglycan II Precursor.

Properties

Applications

Our Abpromise guarantee covers the use of ab35378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/50 - 1/300.
WB Use at an assay dependent dilution. Predicted molecular weight: 40 kDa.

Target

  • FunctionMay affect the rate of fibrils formation.
  • Involvement in diseaseDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
  • Sequence similaritiesBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
    Contains 12 LRR (leucine-rich) repeats.
  • Post-translational
    modifications
    The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bone proteoglycan II antibody
    • CSCD antibody
    • DCN antibody
    • DCN protein antibody
    • Decorin antibody
    • Decorin proteoglycan antibody
    • Dermatan sulphate proteoglycans II antibody
    • DKFZp686J19238 antibody
    • DSPG 2 antibody
    • DSPG2 antibody
    • PG 40 antibody
    • PG II antibody
    • PG S2 antibody
    • PG-S2 antibody
    • PG40 antibody
    • PGII antibody
    • PGS 2 antibody
    • PGS2 antibody
    • PGS2_HUMAN antibody
    • Proteoglycan core protein antibody
    • SLRR1B antibody
    • Small leucine rich protein 1B antibody
    see all

References for Anti-Decorin antibody (ab35378)

This product has been referenced in:
  • Yang G  et al. Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix. Biomaterials 34:9295-306 (2013). WB ; Cow . Read more (PubMed: 24044998) »

See 1 Publication for this product

Product Wall

Thank you for your interest in Abcam's antibodies, particularly anti-mouse decorin antibodies. None of our decorin antibodies have been tested for reactivity with murine decorin but at least one, ab35378, is predicted to react, based on homolog...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"