Overview

  • Product nameAnti-Decorin antibody
    See all Decorin primary antibodies
  • Description
    Goat polyclonal to Decorin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Pig, Macaque Monkey
  • Immunogen

    Synthetic peptide:

    KISRVDAASLKGLNN

    by a Cysteine residue linker, corresponding to internal sequence amino acids 232-246 of Human Decorin (NP_001911.1; NP_598011.1; NP_598012.1)

  • Positive control
    • Human Kidney lysate
  • General notes


    This antibody is expected to recognize the three reported isoforms a, b and c (NP_001911.1; NP_598011.1; NP_598012.1 resp.). Reported variants NP_598010.1 and NP_001911.1 represent identical protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab90425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 40 kDa).

Target

  • FunctionMay affect the rate of fibrils formation.
  • Involvement in diseaseDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
  • Sequence similaritiesBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
    Contains 12 LRR (leucine-rich) repeats.
  • Post-translational
    modifications
    The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bone proteoglycan II antibody
    • CSCD antibody
    • DCN antibody
    • DCN protein antibody
    • Decorin antibody
    • Decorin proteoglycan antibody
    • Dermatan sulphate proteoglycans II antibody
    • DKFZp686J19238 antibody
    • DSPG 2 antibody
    • DSPG2 antibody
    • PG 40 antibody
    • PG II antibody
    • PG S2 antibody
    • PG-S2 antibody
    • PG40 antibody
    • PGII antibody
    • PGS 2 antibody
    • PGS2 antibody
    • PGS2_HUMAN antibody
    • Proteoglycan core protein antibody
    • SLRR1B antibody
    • Small leucine rich protein 1B antibody
    see all

Anti-Decorin antibody images

  • Anti-Decorin antibody (ab90425) at 0.5 µg/ml + Human kidney lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 40 kDa

References for Anti-Decorin antibody (ab90425)

ab90425 has not yet been referenced specifically in any publications.

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The immunogen of antibody ab90425 shows 66.6% homology than ab67449 which shows 83% with mouse sequence. Based on this data I presume ab90425 would be suitable.

Please note we do not have tested these anti...

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Thank you for your enquiry and your interest in our products. The immunogen sequence used to raise this antibody (ab90425) is published under the Immunogen: synthetic peptide: KISRVDAASLKGLNN by a Cysteine residue linker, corresponding to internal s...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"