Overview

  • Product name
  • Description
    Rabbit polyclonal to DECR2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Monkey
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 92-242 of Human DECR2

  • Positive control
    • A549 whole cell lysate; HeLa, HepG2 and HCT116 cells; A549 xenograft

Properties

Applications

Our Abpromise guarantee covers the use of ab153849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 31 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
  • Sequence similarities
    Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
  • Cellular localization
    Peroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2 4 dienoyl CoA reductase 2 antibody
    • 2 4 dienoyl CoA reductase 2 peroxisomal antibody
    • 2 antibody
    • 4-dienoyl-CoA reductase 2 antibody
    • 4-dienoyl-CoA reductase antibody
    • DECR 2 antibody
    • Decr2 antibody
    • DECR2_HUMAN antibody
    • EC 1.3.1.34 antibody
    • pDCR antibody
    • Peroxisomal 2 4 dienoyl CoA reductase antibody
    • Peroxisomal 2 antibody
    • SDR17C1 antibody
    • Short chain dehydrogenase/reductase family 17C member 1 antibody
    see all

Images

  • Anti-DECR2 antibody (ab153849) at 1/1000 dilution + A549 (30 µg of whole cell lysate)

    Predicted band size: 31 kDa

  • Immunohistochemical analysis of paraffin-embedded A549 xenograft using ab153849 antibody at 1:100 dilution

References

ab153849 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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