The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesUsed for absorption control of antiserum binding.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Delta type opioid receptor
Delta type opioid receptor DOR 1
Delta type opioid receptor DOR1
Delta-type opioid receptor
Opioid receptor delta 1
RelevanceFunction: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Tissue specificity: Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.
Similarity: Belongs to the G-protein coupled receptor 1 family.
Ubiquitinated. A basal ubiquitination seems not to be related to degradation. Ubiquitination is increased upon formation of OPRM1:OPRD1 oligomers leading to proteasomal degradation; the ubiquitination is diminished by RTP4.
Cellular localizationMulti pass membrane protein
References for Delta Opioid Receptor peptide (ab38192)
has not yet been referenced specifically in any publications.
Publishing research using ab38192? Please let us know so that we can cite the reference in this datasheet.
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