Overview

  • Product name
    Anti-delta Sarcoglycan antibody
    See all delta Sarcoglycan primary antibodies
  • Description
    Rabbit polyclonal to delta Sarcoglycan
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 37-86 (FVLLLMILIL VNLAMTIWIL KVMNFTIDGM GNLRITEKGL KLEGDSEFLQ) of Mouse delta Sarcoglycan (NP_036021).

  • Positive control
    • Mouse kidney cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • Tissue specificity
    Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
  • Involvement in disease
    Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder.
    Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • Sequence similarities
    Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • Post-translational
    modifications
    Glycosylated.
    Disulfide bonds are present.
  • Cellular localization
    Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • 35 kDa dystrophin associated glycoprotein antibody
    • 35 kDa dystrophin-associated glycoprotein antibody
    • 35DAG antibody
    • CMD1L antibody
    • DAGD antibody
    • Delta-sarcoglycan antibody
    • Delta-SG antibody
    • Dystrophin associated glycoprotein delta sarcoglycan antibody
    • LGMD2F antibody
    • MGC22567 antibody
    • Placental delta sarcoglycan antibody
    • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody
    • SG delta antibody
    • SGCD antibody
    • SGCD_HUMAN antibody
    • SGCDP antibody
    • SGD antibody
    see all

Images

  • Anti-delta Sarcoglycan antibody (ab113813) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 32 kDa

References

ab113813 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab113813.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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