Overview

  • Product name
    Anti-delta Sarcoglycan antibody
    See all delta Sarcoglycan primary antibodies
  • Description
    Rabbit polyclonal to delta Sarcoglycan
  • Tested applications
    Suitable for: WB, ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from an internal region of Human delta Sarcoglycan.

Properties

Applications

Our Abpromise guarantee covers the use of ab92896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ICC
  • Application notes
    ICC: 1/50 - 1/200.
    WB: 1/100 - 1/1000. Predicted molecular weight: 32 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
    • Tissue specificity
      Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
    • Involvement in disease
      Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder.
      Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
    • Sequence similarities
      Belongs to the sarcoglycan beta/delta/gamma/zeta family.
    • Post-translational
      modifications
      Glycosylated.
      Disulfide bonds are present.
    • Cellular localization
      Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
    • Information by UniProt
    • Database links
    • Alternative names
      • 35 kDa dystrophin associated glycoprotein antibody
      • 35 kDa dystrophin-associated glycoprotein antibody
      • 35DAG antibody
      • CMD1L antibody
      • DAGD antibody
      • Delta-sarcoglycan antibody
      • Delta-SG antibody
      • Dystrophin associated glycoprotein delta sarcoglycan antibody
      • LGMD2F antibody
      • MGC22567 antibody
      • Placental delta sarcoglycan antibody
      • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody
      • SG delta antibody
      • SGCD antibody
      • SGCD_HUMAN antibody
      • SGCDP antibody
      • SGD antibody
      see all

    References

    This product has been referenced in:

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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