Anti-Dengue Virus NS1 glycoprotein antibody [B1427M] (ab151179)

Overview

  • Product name
    Anti-Dengue Virus NS1 glycoprotein antibody [B1427M]
    See all Dengue Virus NS1 glycoprotein primary antibodies
  • Description
    Mouse monoclonal [B1427M] to Dengue Virus NS1 glycoprotein
  • Tested applications
    Suitable for: Sandwich ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Dengue virus 1, Dengue virus 2, Dengue virus 3, Dengue virus 4
  • Immunogen

    Recombinant Dengue Virus NS1 (mixture of serotypes 1, 2, 3 and 4).

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. We would recommend antibody ab41616 as a replacement.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at +4°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.20
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    ab151179 is > 90% pure.
  • Clonality
    Monoclonal
  • Clone number
    B1427M
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab151179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [B1424M] to Dengue Virus NS1 glycoprotein (ab138696).
ICC/IF Use at an assay dependent concentration.

Target

  • Relevance
    NS1 is one of 7 Dengue Virus non-structural proteins which are thought to be involved in viral replication. NS1 exists as a monomer in its immature form but is rapidly processed in the endoplasmic reticulum to form a stable dimer. A small amount of NS1 remains associated with intracellular organelles where it is thought to be involved in viral replication. The rest of NS1 is found either associated with the plasma membrane or secreted as a soluble hexadimer. NS1 is essential for viral viability but its precise biological function is unknown. Antibodies raised in response to NS1 in viral infection can cross react with cell surface antigens on epithelial cells and platelets and this has been implicated in the development of Dengue Hemorrhagic fever.
  • Database links
    • Alternative names
      • Dengue NS1 antibody
      • Dengue Virus non structural protein 1 antibody

    References

    ab151179 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Regarding the sandwich ELISA antibody pair for Dengue NS1, we are adding the antibody that pairs with ab138696. The catalogue number is ab151179 and we expect it will be available in about two weeks.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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