Anti-Density Regulated Protein antibody (ab108221)
Key features and details
- Rabbit polyclonal to Density Regulated Protein
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-Density Regulated Protein antibody
See all Density Regulated Protein primary antibodies -
Description
Rabbit polyclonal to Density Regulated Protein -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Rainbow trout, Orangutan, Xenopus tropicalis -
Immunogen
Synthetic peptide corresponding to a region between amino acids 148 - 198 of Human Density Regulated Protein (NP_003668.2).
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Positive control
- HeLa, 293T or NIH 3T3 whole cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: Tris citrate/phosphate -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab108221 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/2000 - 1/10000. Predicted molecular weight: 22 kDa.
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Notes |
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WB
1/2000 - 1/10000. Predicted molecular weight: 22 kDa. |
Target
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Function
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. -
Tissue specificity
Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney. -
Sequence similarities
Belongs to the DENR family.
Contains 1 SUI1 domain. - Information by UniProt
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Database links
- Entrez Gene: 771794 Chicken
- Entrez Gene: 614238 Cow
- Entrez Gene: 8562 Human
- Entrez Gene: 68184 Mouse
- Entrez Gene: 360806 Rat
- Entrez Gene: 444615 Xenopus laevis
- Omim: 604550 Human
- SwissProt: Q5ZJ39 Chicken
see all -
Alternative names
- denr antibody
- DENR_HUMAN antibody
- Density regulated protein antibody
see all
Images
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All lanes : Anti-Density Regulated Protein antibody (ab108221) at 0.1 µg/ml
Lane 1 : Hela whole cell lysate at 50 µg
Lane 2 : Hela whole cell lysate at 15 µg
Lane 3 : Hela whole cell lysate at 5 µg
Lane 4 : 293T whole cell lysate at 50 µg
Lane 5 : NIH 3T3 whole cell lysate at 50 µg
Developed using the ECL technique.
Predicted band size: 22 kDa
Exposure time: 30 seconds
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab108221 has been referenced in 1 publication.
- Castelo-Szekely V et al. Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock. Nucleic Acids Res 47:5193-5209 (2019). PubMed: 30982898