Overview

  • Product name
  • Description
    Rabbit polyclonal to DENTT
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Cynomolgus monkey, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 643-693 of Human DENTT (NP_071400.1).

  • Positive control
    • HeLa, 293T and Jurkat whole cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab168860 was affinity purified using an epitope specific to DENTT immobilized on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab168860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 79 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
    • Tissue specificity
      Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
    • Sequence similarities
      Belongs to the nucleosome assembly protein (NAP) family.
    • Post-translational
      modifications
      Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
    • Cellular localization
      Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons.
    • Information by UniProt
    • Database links
    • Alternative names
      • CASK interacting nucleosome assembly protein antibody
      • CDA1 antibody
      • Cell division autoantigen 1 antibody
      • CINAP antibody
      • CTCL antibody
      • CTCL tumor antigen se20 4 antibody
      • CTCL-associated antigen se20-4 antibody
      • Cutaneous T cell lymphoma associated antigen se20 4 antibody
      • Cutaneous T cell lymphoma associated tumor antigen se20 4 antibody
      • Cutaneous T-cell lymphoma-associated antigen se20-4 antibody
      • Differentially Expressed Nucleolar TGF beta1 Target antibody
      • Differentially Expressed Nucleolar TGF beta1 Target protein antibody
      • Differentially-expressed nucleolar TGF-beta1 target protein antibody
      • HRIHFB2216 antibody
      • NP79 antibody
      • Nuclear protein of 79 kDa antibody
      • RP1 290F12.2 antibody
      • SE20 4 antibody
      • SE204 antibody
      • Testis specific protein Y encoded like 2 antibody
      • testis-specific protein Y encoded-like 2 antibody
      • Testis-specific Y-encoded-like protein 2 antibody
      • TSPX antibody
      • TSPY like 2 antibody
      • TSPY like protein 2 antibody
      • TSPY-like protein 2 antibody
      • TSPYL2 antibody
      • TSYL2_HUMAN antibody
      see all

    Images

    • All lanes : Anti-DENTT antibody (ab168860) at 0.4 µg/ml

      Lane 1 : HeLa whole cell lysate
      Lane 2 : 293T whole cell lysate
      Lane 3 : Jurkat whole cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique.

      Predicted band size: 79 kDa


      Exposure time: 3 minutes

    References

    ab168860 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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