Overview

  • Product name
    Deoxyarbutin
  • Description
    Potent reversible tyrosinase inhibitor
  • Biological description
    Potent reversible tyrosinase inhibitor (IC50 = 50 nM). Generates minimal amounts of ROS. Inhibits melanogenesis in vivo.
  • Purity
    > 99%

Properties

  • Chemical name
    4-(Oxan-2-yloxy)phenol
  • Molecular weight
    194.23
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C11H14O3
  • CAS Number
    53936-56-4
  • PubChem identifier
    11745519
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in ethanol to 100 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    C1CCOC(C1)OC2=CC=C(C=C2)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Chawla S  et al. DeoxyArbutin and its derivatives inhibit tyrosinase activity and melanin synthesis without inducing reactive oxygen species or apoptosis. J Drugs Dermatol 11:e28-34 (2012). Read more (PubMed: 23134995) »
  • Hamed SH  et al. Effect of deoxyarbutin on melanogenesis: in vivo comparison with other melanogenesis inhibitor. J Cosmet Sci 55:118-9 (0). Read more (PubMed: 15065582) »
  • Hamed SH  et al. Comparative efficacy and safety of deoxyarbutin, a new tyrosinase-inhibiting agent. J Cosmet Sci 57:291-308 (0). Read more (PubMed: 16957809) »

See 0 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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