• Product nameAnti-Desmocollin 2 antibody
    See all Desmocollin 2 primary antibodies
  • Description
    Rabbit polyclonal to Desmocollin 2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Dog, Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 480-676 of Human Desmocollin 2 isoform 2A and 2B (Uniprot ID = Q02487).

  • Positive control
    • 293T, A431, H1299, HeLa, MOLT4 and Raji lysates. OVCAR3 xenograft (IHC)



Our Abpromise guarantee covers the use of ab95967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 94 kDa.
IHC-P 1/100 - 1/500.


  • FunctionComponent of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
  • Tissue specificityExpressed in epithelia, myocardium and lymph nodes.
  • Involvement in diseaseDefects in DSC2 are the cause of familial arrhythmogenic right ventricular dysplasia type 11 (ARVD11) [MIM:610476]; also known as arrhythmogenic right ventricular cardiomyopathy 11 (ARVC11). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • Sequence similaritiesContains 5 cadherin domains.
  • DomainCalcium may be bound by the cadherin-like repeats.
  • Cellular localizationCell membrane. Cell junction > desmosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARVD11 antibody
    • Cadherin family member 2 antibody
    • CDHF2 antibody
    • Desmocollin 3 antibody
    • Desmocollin-2 antibody
    • Desmocollin-3 antibody
    • Desmocollin2 antibody
    • Desmosomal glycoprotein II and III antibody
    • Desmosomal glycoprotein II antibody
    • Desmosomal glycoprotein II/III antibody
    • Desmosomal glycoprotein III antibody
    • DG2 antibody
    • DGII/III antibody
    • DKFZp686I11137 antibody
    • DSC 2 antibody
    • DSC2 antibody
    • DSC2_HUMAN antibody
    • DSC3 antibody
    see all

Anti-Desmocollin 2 antibody images

  • Anti-Desmocollin 2 antibody (ab95967) at 1/500 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 94 kDa
  • ab95967 at 1/500 dilution staining Desmocollin 2 in paraffin-embedded OVCAR3 xenograft by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

References for Anti-Desmocollin 2 antibody (ab95967)

This product has been referenced in:
  • Resnik N  et al. Desmosome assembly and cell-cell adhesion are membrane raft-dependent processes. J Biol Chem 286:1499-507 (2011). WB ; Dog . Read more (PubMed: 21071449) »

See 1 Publication for this product

Product Wall

Application Western blot
Sample Mouse Cell lysate - whole cell (Epithelial Organoids)
Gel Running Conditions Reduced Denaturing (BioRad 4-15% TGX gel)
Loading amount 10 µg
Specification Epithelial Organoids
Blocking step Odyssey Blocking Buffer as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 100% · Temperature: 20°C

Mrs. Amanda Fairchild

Verified customer

Submitted Aug 03 2015

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step Dako serum free protein block as blocking agent for 30 minute(s) · Concentration: 0.25%
Antigen retrieval step Heat mediated
Sample Monkey Tissue sections (vagina)
Specification vagina
Permeabilization No
Fixative Paraformaldehyde

Abcam user community

Verified customer

Submitted Nov 25 2013