• Product nameAnti-Desmocollin 3 antibody
    See all Desmocollin 3 primary antibodies
  • Description
    Rabbit polyclonal to Desmocollin 3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide: MQENSLGPFP LFLQQVESDA AQNYTVFYSI SGRGVDKEPL NLFYIERDTG , corresponding to a region within N terminal amino acids 143 - 192 of Human Desmocollin 3 (NP_001932)

  • Positive control
    • Jurkat cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab84709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 100 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionComponent of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
  • Tissue specificityEpidermis, buccal mucosa, esophagus and cervix.
  • Involvement in diseaseDefects in DSC3 are the cause of hypotrichosis and recurrent skin vesicles (HRSV) [MIM:613102]. A disorder characterized by hypotrichosis and the appearance of recurrent skin vesicle formation. Affected individuals show sparse and fragile hair on scalp, as well as absent eyebrows and eyelashes. Vesicles filled with thin, watery fluid are observed on the scalp and skin of most of the boby. Mucosal vesicles are absent.
  • Sequence similaritiesContains 5 cadherin domains.
  • DomainCalcium may be bound by the cadherin-like repeats.
  • Cellular localizationCell membrane. Cell junction > desmosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cadherin family member 3 antibody
    • CDHF3 antibody
    • desmocollin 3a/3b antibody
    • Desmocollin 4 antibody
    • Desmocollin-3 antibody
    • Desmocollin-4 antibody
    • Desmocollin3 antibody
    • Desmocollin4 antibody
    • DSC antibody
    • DSC1 antibody
    • DSC2 antibody
    • DSC3 antibody
    • DSC3_HUMAN antibody
    • DSC4 antibody
    • HT CP antibody
    • HT-CP antibody
    • HTCP antibody
    see all

Anti-Desmocollin 3 antibody images

  • Anti-Desmocollin 3 antibody (ab84709) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 100 kDa
    Observed band size : 85 kDa (why is the actual band size different from the predicted?)

References for Anti-Desmocollin 3 antibody (ab84709)

ab84709 has not yet been referenced specifically in any publications.

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