Anti-Desmoglein 1 antibody (ab122913)

Overview

  • Product nameAnti-Desmoglein 1 antibody
    See all Desmoglein 1 primary antibodies
  • Description
    Goat polyclonal to Desmoglein 1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human Desmoglein 1.

  • Positive control
    • Human Skin tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab122913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • FunctionComponent of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • Tissue specificityEpidermis, tongue, tonsil and esophagus.
  • Involvement in diseaseDefects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.
  • Sequence similaritiesContains 4 cadherin domains.
  • DomainCalcium may be bound by the cadherin-like repeats.
  • Cellular localizationCell membrane. Cell junction > desmosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cadherin family member 4 antibody
    • CDHF4 antibody
    • Desmoglein-1 antibody
    • Desmosomal glycoprotein 1 antibody
    • DG1 antibody
    • DGI antibody
    • DSG antibody
    • DSG1 antibody
    • DSG1_HUMAN antibody
    • EPKHE antibody
    • EPKHIA antibody
    • Pemphigus foliaceus antigen antibody
    • PPKS1 antibody
    • SPPK1 antibody
    see all

Anti-Desmoglein 1 antibody images

  • ab122913, at 3.75 µg/ml, staining Desmoglein 1 in Formalin-fixed, Paraffin-embedded Human Skin tissue by Immunohistochemistry.

References for Anti-Desmoglein 1 antibody (ab122913)

ab122913 has not yet been referenced specifically in any publications.

Product Wall

Merci beaucoup pour votre requete. Veuillez trouver les MSDS en document attaché. Comme ces deux anticorps contiennent de l'azide, ces fiches sont relatives à ceci. Pour ces anticorps, ces fiches MSDS peuvent aussi etre directement téléchargées de la f...

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