Anti-Desmoglein 2 antibody (ab96761)


  • Product name
    Anti-Desmoglein 2 antibody
    See all Desmoglein 2 primary antibodies
  • Description
    Rabbit polyclonal to Desmoglein 2
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 1 and 176 of Desmoglein 2 (NP_001934).

  • Positive control
    • WB: 293T, H1299 and MOLT4 whole cell lysates; HepG2 cell lysate IHC-P: DU145 xenograft



Our Abpromise guarantee covers the use of ab96761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 122 kDa.
IHC-P 1/100 - 1/500.


  • Function
    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • Tissue specificity
    All of the tissues tested and carcinomas.
  • Involvement in disease
    Defects in DSG2 are the cause of familial arrhythmogenic right ventricular dysplasia type 10 (ARVD10) [MIM:610193]; also known as arrhythmogenic right ventricular cardiomyopathy 10 (ARVC10). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
    Genetic variations in DSG2 are the cause of susceptibility to cardiomyopathy dilated type 1BB (CMD1BB) [MIM:612877]. A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • Sequence similarities
    Contains 4 cadherin domains.
  • Domain
    Calcium may be bound by the cadherin-like repeats.
  • Cellular localization
    Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARVC 10 antibody
    • ARVC10 antibody
    • ARVD 10 antibody
    • ARVD10 antibody
    • Cadherin family member 5 antibody
    • CDHF 5 antibody
    • CDHF5 antibody
    • CMD1BB antibody
    • Desmoglein 2 antibody
    • Desmoglein-2 antibody
    • Desmoglein2 antibody
    • DSG 2 antibody
    • DSG2 antibody
    • DSG2_HUMAN antibody
    • HDGC antibody
    • HDGC included antibody
    • Human Desmoglein colon antibody
    • MGC117034 antibody
    • MGC117036 antibody
    • MGC117037 antibody
    see all


  • All lanes : Anti-Desmoglein 2 antibody (ab96761) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : MOLT4 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 122 kDa
  • Immunohistochemical analysis of Desmoglein 2 in paraffin embedded DU145 xenograft, using ab96761 at a 1/100 dilution.


ab96761 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Vielen Dank für Ihre Geduld. Ich kann Ihnen jetzt auch bestätigen, dass der ab14415 ein Epitop auf dem extrazellulären Part des Desmoglein 2 erkennt. Auch der ab96761 erkennt das extrazelluläre Desmoglein 2, da der Antikörper gegen ein rekombina...

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