Anti-Desmoglein 3 antibody [MM0245- 4W25] (ab89177)

Overview

  • Product nameAnti-Desmoglein 3 antibody [MM0245- 4W25]
    See all Desmoglein 3 primary antibodies
  • Description
    Mouse monoclonal [MM0245- 4W25] to Desmoglein 3
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length human Desmoglein 3 protein.

  • General notesThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized mouse).

Properties

Applications

Our Abpromise guarantee covers the use of ab89177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 108 kDa.
IHC-P 1/20 - 1/100.

Target

  • FunctionComponent of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • Tissue specificityEpidermis, tongue, tonsil, esophagus and carcinomas.
  • Sequence similaritiesContains 4 cadherin domains.
  • DomainThree calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
  • Cellular localizationCell membrane. Cell junction > desmosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • 130 kD pemphigus vulgaris antigen antibody
    • 130 kDa pemphigus vulgaris antigen antibody
    • Balding antibody
    • Cadherin family member 6 antibody
    • CDHF 6 antibody
    • CDHF6 antibody
    • Desmoglein 3 antibody
    • Desmoglein 3 precursor antibody
    • Desmoglein-3 antibody
    • Desmoglein3 antibody
    • DKFZp686P23184 antibody
    • DSG 3 antibody
    • DSG3 antibody
    • DSG3_HUMAN antibody
    • Pemphigus vulgaris antigen antibody
    • PVA antibody
    see all

Anti-Desmoglein 3 antibody [MM0245- 4W25] images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling Desmoglein 3 with ab89177. Tissue was treated with 15µg/ml Protenase K for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

References for Anti-Desmoglein 3 antibody [MM0245- 4W25] (ab89177)

ab89177 has not yet been referenced specifically in any publications.

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