• Product nameAnti-DFNB31 antibody
    See all DFNB31 primary antibodies
  • Description
    Rabbit polyclonal to DFNB31
  • Specificityab106980 will not recognise isoform 2.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 385-413 of Human DFNB31 (NP_056219.3, NP_001077354.2, NP_001166896.1).

  • Positive control
    • K562 cell lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab106980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 97 kDa.


  • FunctionNecessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear.
  • Involvement in diseaseDefects in WHRN are the cause of deafness autosomal recessive type 31 (DFNB31) [MIM:607084]. DFNB31 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
    Defects in WHRN are the cause of Usher syndrome type 2D (USH2D) [MIM:611383]. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa and sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH2 is characterized by congenital mild hearing impairment with normal vestibular responses.
  • Sequence similaritiesContains 3 PDZ (DHR) domains.
  • Cellular localizationCytoplasm. Cell projection > stereocilium. Cell projection > growth cone. Detected at the level of stereocilia in inner outer hair cells of the cochlea and vestibule. Co-localizes with the growing ends of actin filaments (By similarity). Colocalizes with MPP1 in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium.
  • Information by UniProt
  • Database links
  • FormThere are 4 isoforms produced by alternative splicing.
  • Alternative names
    • 1110035G07Rik antibody
    • Autosomal recessive deafness type 31 protein antibody
    • CASK interacting protein CIP98 antibody
    • CIP 98 antibody
    • CIP98 antibody
    • Deafness autosomal recessive 31 antibody
    • DFNB 31 antibody
    • DKFZp434N014 antibody
    • KIAA1526 antibody
    • RP11 9M16.1 antibody
    • USH 2D antibody
    • USH2D antibody
    • Whirlin antibody
    • WHRN antibody
    • WHRN_HUMAN antibody
    • WI antibody
    see all

Anti-DFNB31 antibody images

  • Anti-DFNB31 antibody (ab106980) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 97 kDa

References for Anti-DFNB31 antibody (ab106980)

ab106980 has not yet been referenced specifically in any publications.

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