Overview

  • Product name
    Anti-DGAT2L3 antibody
  • Description
    Rabbit polyclonal to DGAT2L3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 (NWCVWTHIRD YFPITILKTK DLSPEHNYLM GVHPHGLLTF GAFCNFCTEA) of Human DGAT2L3 (NP_001013597).

  • Positive control
    • Human fetal stomach lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab104855 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20).
  • Tissue specificity
    Predominantly expressed in skin, where it is limited to the sebaceous gland. Expressed in more mature, centrally located cells just before their rupture and sebum release. Also expressed in all tissues except spleen. Expressed at higher level in thymus, prostate and testis.
  • Sequence similarities
    Belongs to the diacylglycerol acyltransferase family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acyl-CoA wax alcohol acyltransferase 1 antibody
    • Awat1 antibody
    • AWAT1_HUMAN antibody
    • DGA antibody
    • DGA2 antibody
    • Diacyl glycerol acyltransferase 2 antibody
    • Diacylglycerol acyltransferase 2 antibody
    • Diacylglycerol O acyltransferase 2 like 3 antibody
    • Diacylglycerol O-acyltransferase 2-like protein 3 antibody
    • Long-chain-alcohol O-fatty-acyltransferase 1 antibody
    see all

Images

  • Anti-DGAT2L3 antibody (ab104855) at 1 µg/ml + Human fetal stomach lysate at 10 µg

    Predicted band size : 38 kDa

References

ab104855 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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